That would depend upon what was more important...human life or human religious dogma.
Well, I guess that obviously means that you don't think any follower of the God of the Bible, or follower of Jesus is rational then.
The Hebrew boys given the Babylonian names Shadrach, Meshach, and Abednego refused to bow to an idol, at the cost of their lives - being incinerated - not cooked - in a furnace.
Daniel refused to stop praying to his God, even though it meant being thrown to hungry lions.
Jesus said that anyone who isn't willing to die for his sake, and the sake of the good news, is not approved by him, or his father.
Many were willing to did by wild beast, just for having an unpopular belief - just being a Christian, or possessing a Bible.
There are hundreds of examples of men and women who were willing to die for what they believed.
Some do it because they have faith in God, and his promises.
Some do it for different reasons.
For example men and women are willing to go to war, and fight for a nation - even at the cost of their limbs, and life.
Men and women are willing to get into a vehicle and race around a track - at the risk of their lives.
The difference between this worldly view, and the believer, is that while those of the world give up their lives for their beliefs - they do so without hope - except the hope that they don't die, which they are not sure of.
The believer though, has faith that what he hopes for is sure. His faith is like an anchor for him/her - They are unwavering. The believe the promises of God are sure, and they base this on the evidence they have. Hebrews 11
I consider them rational - myself included. In fact, I consider it more rational to have a belief that one believes to be sound, than those who are willing to kill people for what they believe, or restrict them from exercising their right of choice - provided they are not murdering or raping anyone, or torturing someone.