belief in science is a necessary thing too; otherwise there is no innovation, no change.
in enlightenment there is a release from attachment in discovering the new. works the same way in science the old way of thinking doesn't necessarily work in the new way of understanding the unknown.
so materialism isn't as important as the mind. you only use what you need in order to understand what you don't. in real science the ideal is understood only after an idea is realized.
so it is the mind that first seeks and then finds. what the eye can't observe the mind's eye can still discover by changing the instruments used to find it.
so again it is the spiritual that is more powerful than the material
According to materialism your mind is also made of matter, more specifically it's made of your neuro-chemical network. Note that mental processes and structures are all under the perview of science. If you want to refer to the enlightenment ideas, it's the idea that reason, science and materialism are to be used to reach humanist goals which includes self realisation, harmony, freedom, etc.
If you prefer the more vague and orientalist vision of "enlightenment", as a state of harmony, inner peace and self realisation and awe, then yes Jesus talked about this state, but did not make reaching such a state of mind a central theme or end goal of his teachings. He was more pre-occupied with human behaviors and love of God than personnal growth.