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How much DNA we share with everything

Shadow Wolf

Certified People sTabber
Damn cats! They share 90% of our DNA and they think they rule over us and all our stuff belongs to them.
 

Jumi

Well-Known Member
It's hard not to share DNA when you have common ancestors. :) It's interesting to think, how little has changed in the process from one species to next.
 

BSM1

What? Me worry?
No offense, but you never know when you're going to need all of your DNA, so I'm not sharing any of mine.
 

Brickjectivity

wind and rain touch not this brain
Staff member
Premium Member
Question: What does it mean to share 60% in common? How is that measured? I mean, does it not depend upon how you define commonality?

One would assume that they find common strands and then cross them out, but maybe that is not what they are doing, and maybe it depends upon the length. It would be harder to find a match if you limited the comparison to very long strings of DNA. Another thing is, the DNA strands are not the same length, so how can you use a percentage in a meaningful way?
 

SabahTheLoner

Master of the Art of Couch Potato Cuddles
Question: What does it mean to share 60% in common? How is that measured? I mean, does it not depend upon how you define commonality?

One would assume that they find common strands and then cross them out, but maybe that is not what they are doing, and maybe it depends upon the length. It would be harder to find a match if you limited the comparison to very long strings of DNA. Another thing is, the DNA strands are not the same length, so how can you use a percentage in a meaningful way?

There are many, many genes within an animal, so a 99% difference is actually quite a bit of a difference. A group of scientists actually sequenced an entire human genome and printed the sequence in books. They required several bookshelfs filled with encyclopedia-sized books to physically store only one gene sequence on paper. Keep in mind that gene sequencing isn't a complicated process; you only have four neucleobases (C, G, A, T) and unless you have a mutation they come in predictable pairs. Most of the challenge comes in size.

If something is a mammal, chances are that just because of that detail we will share a large number of genes with it. The genes that can be found across animals can form links to common ancestors. Despite the different number of chromosomes each species has (humans have 23 pairs, mice have 20 pairs, elephants have 28 pairs and mosquitoes have only 3 pairs) with gene sequencing a pattern can be seen in when comparing the genes, so to humans a banana might share a large number of genes, but given that humans have 46 chromosomes that are paired and bananas usually have 33 chromosomes that are in groups of three, comparing genes is mostly proof of evolution. However what can be helpful is when the genes compared can lead to medical advances.

The reason many heart patients can receive baboon and pig hearts instead of a human one as a replacement is because we share an overwhelming genetic similarity to those species. In fact it's a growing practice to grow transplanted organs with specific human genetic sequences (usually transmitted via a man-made non-lethal virus containing the genes) in pigs for a short amount of time so a patient's body is more likely to accept the oragan compared to just having a pig heart with similar genetics but a vastly different sequencing. The latter donor is more likely to be rejected by the body, but it's still a higher success rate compared to other animal hearts because of the similar genetics.

(You can probably tell by my answer that I really like reading about genetics.)
 

Polymath257

Think & Care
Staff member
Premium Member
Did you know we share about 60% of our genes with bananas? How bizarre of a thought!

Anyway I came across this thinking about DNA similarities again and I think it's amazing how much we're actually related to.

Our DNA is 99.9% the same as the person sitting next to us — and we're surprisingly similar to a bunch of other living things

Yes, bananas and us are both eucaryotic organisms. Much of the basic metabolism is the same: use of DNA as a genetic material, the use of RNA for protein synthesis, many of the same organelles in the cells, use of sugars for energy, use of mitochondria for production of ATP, etc.

Obviously, there are differences also. But they are for more large scale organization rather than fundamental biochemistry. There will be differences because of the chloroplasts and the cell wall (instead of just a membrane), and photosynthesis uses some good mechanisms. But *most* of the genes are dealing with more low level aspects. The large scale stuff tends to be controlled by relatively few genes.
 

ChristineM

"Be strong", I whispered to my coffee.
Premium Member
Explains why I've been called a blooming idiot...just sayin'.

Bringing back flower power one dna molecule at a time.

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