1. Welcome to Religious Forums, a friendly forum to discuss all religions in a friendly surrounding.

    Your voice is missing! You will need to register to get access to the following site features:
    • Reply to discussions and create your own threads.
    • Our modern chat room. No add-ons or extensions required, just login and start chatting!
    • Access to private conversations with other members.

    We hope to see you as a part of our community soon!

Origin of life insight: Peptides can form without amino acids

Discussion in 'Science and Technology' started by Wandering Monk, Jul 12, 2019.

  1. Wandering Monk

    Wandering Monk Well-Known Member

    Joined:
    Apr 14, 2019
    Messages:
    1,252
    Ratings:
    +721
    Religion:
    agnostic
    • Informative Informative x 5
    • Like Like x 3
  2. Road Less Traveled

    Road Less Traveled Active Member

    Joined:
    Jun 27, 2019
    Messages:
    482
    Ratings:
    +109
    From link:
    ‘They found that aminonitriles have the innate reactivity to achieve peptide bond formation in water with greater ease than amino acids.’

    That could potentially solve the amino acid’s being unable to randomly bond well in water issue. As also suggested from the link were struggles with the central focus on only amino acids.
     
    • Informative Informative x 2
  3. shunyadragon

    shunyadragon Veteran Member
    Premium Member

    Joined:
    Mar 23, 2017
    Messages:
    12,282
    Ratings:
    +5,604
    Religion:
    Baha'i Faith
    Neat reference to an advance in the science of abiogenesis.
     
    • Like Like x 1
  4. Stevicus

    Stevicus Well-Known Member
    Premium Member

    Joined:
    Sep 26, 2011
    Messages:
    9,396
    Ratings:
    +4,653
    Religion:
    Agnostic
    I'll have a cellular peptide cake, with mint frosting.
     
    • Funny Funny x 2
  5. Bob the Unbeliever

    Bob the Unbeliever Well-Known Member

    Joined:
    Mar 19, 2017
    Messages:
    6,702
    Ratings:
    +4,180
    Religion:
    unbeliever
    Interesting read. Thanks!
     
  6. exchemist

    exchemist Well-Known Member

    Joined:
    Apr 24, 2018
    Messages:
    4,677
    Ratings:
    +3,466
    Religion:
    RC (culturally at least)
    Yes indeed. The Nature abstract is here for anyone wanting a more technical take on it:
    Peptide ligation by chemoselective aminonitrile coupling in water

    The key sentence seems to be this : " Here we report a chemoselective, high-yielding α-aminonitrile ligation that exploits only prebiotically plausible molecules—hydrogen sulfide, thioacetate12,14 and ferricyanide12,14,15,16,17 or cyanoacetylene8,14—to yield α-peptides in water."

    It all seems to revolve around thioesters, which is appealing as they are implicated in other biochemical processes too.
     
    • Winner Winner x 1
    • Informative Informative x 1
  7. sayak83

    sayak83 Well-Known Member
    Staff Member Premium Member

    Joined:
    May 7, 2012
    Messages:
    8,580
    Ratings:
    +8,044
    Religion:
    Pluralist Hindu
    Yes. Things are going quite well. I am thinking on starting a research project on abiogenesis chemistry as well in a few years time. :)
     
    • Like Like x 1
Loading...