Well...I was surprised that Ben Shapiro was interested in the medical effects of the hormonal pill on woman.
Honestly I realize (despite his capability of pronouncing ten words every 3 seconds or so
Biochemists have been studying women's natural hormones for decades. Since very, very long time.
They have been capable of replicating these hormones in lab and they do work perfectly.
I don't think hormonal pills can have any side effect in the long run.