This thread OP is a twitter thread that is really about intersex people. But it also plays to those who throw around "biological sex" without knowing what they are talking about: Among other reasons, I don't think people know how many transgender people actually are intersex and don't know it. If nothing else, this deals with the "there are only two sexes: male and female" because that's just plain provably wrong.
‘Biological Sex’ Explanation By Bio Professor Goes Viral, Challenging Sex And Identity Discrimination
Also, the twitter thread: https://twitter.com/RebeccaRHelm/status/1207835597206937600
Turns out there is only ONE GENE on the Y chromosome that really matters to sex. It’s called the SRY gene. During human embryonic development the SRY protein turns on male-associated genes. Having an SRY gene makes you “genetically male”. But is this “biological sex”?
Sometimes that SRY gene pops off the Y chromosome and over to an X chromosome. Surprise! So now you’ve got an X with an SRY and a Y without an SRY. What does this mean?
A Y with no SRY means physically you’re female, chromosomally you’re male (XY) and genetically you’re female (no SRY). An X with an SRY means you’re physically male, chromsomally female (XX) and genetically male (SRY). But biological sex is simple! There must be another answer...
...if you’re developing, your body may not produce enough hormones for your genetic sex. Leading you to be genetically male or female, chromosomally male or female, hormonally non-binary, and physically non-binary. Well, except cells have something to say about this...
Maybe cells are the answer to “biological sex”?? Right?? Cells have receptors that “hear” the signal from sex hormones. But sometimes those receptors don’t work. Like a mobile phone that’s on “do not disturb’. Call and cell, they will not answer.
It means you may be genetically male or female, chromosomally male or female, hormonally male/female/non-binary, with cells that may or may not hear the male/female/non-binary call, and all this leading to a body that can be male/non-binary/female.
‘Biological Sex’ Explanation By Bio Professor Goes Viral, Challenging Sex And Identity Discrimination
Also, the twitter thread: https://twitter.com/RebeccaRHelm/status/1207835597206937600
Turns out there is only ONE GENE on the Y chromosome that really matters to sex. It’s called the SRY gene. During human embryonic development the SRY protein turns on male-associated genes. Having an SRY gene makes you “genetically male”. But is this “biological sex”?
Sometimes that SRY gene pops off the Y chromosome and over to an X chromosome. Surprise! So now you’ve got an X with an SRY and a Y without an SRY. What does this mean?
A Y with no SRY means physically you’re female, chromosomally you’re male (XY) and genetically you’re female (no SRY). An X with an SRY means you’re physically male, chromsomally female (XX) and genetically male (SRY). But biological sex is simple! There must be another answer...
...if you’re developing, your body may not produce enough hormones for your genetic sex. Leading you to be genetically male or female, chromosomally male or female, hormonally non-binary, and physically non-binary. Well, except cells have something to say about this...
Maybe cells are the answer to “biological sex”?? Right?? Cells have receptors that “hear” the signal from sex hormones. But sometimes those receptors don’t work. Like a mobile phone that’s on “do not disturb’. Call and cell, they will not answer.
It means you may be genetically male or female, chromosomally male or female, hormonally male/female/non-binary, with cells that may or may not hear the male/female/non-binary call, and all this leading to a body that can be male/non-binary/female.