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Russia has a vaccine

McBell

Resident Sourpuss
Russia is taking a big gamble pushing through "approval" of alleged vaccine before finishing the basic testing.
 

Quetzal

A little to the left and slightly out of focus.
Premium Member
I applaud the attempt to be first but this is concerning:
Moscow’s decision to grant approval before then has raised concerns among some experts. Only about 10% of clinical trials are successful and some scientists fear Moscow may be putting national prestige before safety.
 

Heyo

Veteran Member
So what do you think, health experts say it came out too early.
There are usually three steps before approving a drug or vaccine.
1. Trial: with just a few healthy volunteers it is tested if there are unwanted side effects. The Russian vaccine has passed this test.
2. Trial: with some more volunteers it is tested if the drug/vaccine has the wanted effects, iow if it works. The Russian vaccine has passed this test.
3. Trial: repeat trial #2 but with a greater number (> 1000 participants) and check for rare side effects and establish that it works even better.
The Russian vaccine has not passed this test.
 

Onoma

Active Member
Not to be a Debbie Downer, but we should keep in mind that a vaccine is not a cure-all

Even yearly flu vaccines have a limited success rate ( 40%-60% )
 

sun rise

The world is on fire
Premium Member
Not to be a Debbie Downer, but we should keep in mind that a vaccine is not a cure-all

Even yearly flu vaccines have a limited success rate ( 40%-60% )

And of course even if the success rate is 99%, we have a large contingent of anti-vax wingnuts who will ensure only partial coverage.

Prevention + treatment will in the end be what we have.
 

Onoma

Active Member
And of course even if the success rate is 99%, we have a large contingent of anti-vax wingnuts who will ensure only partial coverage.

Prevention + treatment will in the end be what we have.

Very true, I've noticed there are even people attempting to claim it is the Biblical " mark of the beast " ( Laughable for a number of reasons )

:p
 

epronovost

Well-Known Member
Not to be a Debbie Downer, but we should keep in mind that a vaccine is not a cure-all

Even yearly flu vaccines have a limited success rate ( 40%-60% )

The flu vaccin has a very low efficiency rate compared to other vaccine due to the fact that the flu virus is highly mutable and there are many strains of the flu virus active at any given moment. That's also why we need a new one each year. COVID-19 is a single virus that has been found to not be remarcably mutable. we could expect a higher rate of success for a COVID-19 virus than for the seasonnal flu.
 

Vinayaka

devotee
Premium Member
We'll see the worst of nationalism. "If it ain't made in _________, then foh sho it ain't no good!"

"If it ain't a Hahley, it ain't a bike!"

lol

Individual governments will all do their own individual tests on such things, or trust the other countries that they already trust, But anyone would be a plain fool to refuse to use a product on the basis of its country of origin, rather than whether or not its a good product.
 

Onoma

Active Member
The flu vaccin has a very low efficiency rate compared to other vaccine due to the fact that the flu virus is highly mutable and there are many strains of the flu virus active at any given moment. That's also why we need a new one each year. COVID-19 is a single virus that has been found to not be remarcably mutable. we could expect a higher rate of success for a COVID-19 virus than for the seasonnal flu.

Correct me if I'm wrong here, but we currently deal with about 130 serotypes of influenza, some of which have been with us for many years

In comparison there are 4311 different genomes of Covid-19 that have been sampled just between the dates of Dec 2019 and Aug 2020, all stemming from that one initial genome in Wuhan

You don't think that's going to greatly complicate vaccine development ?

I do, personally, I also know there are many different approaches to the design of the vaccines ( 130+ different vaccines in development )

And not remarkably mutable ?....I was under the impression that coronavirus mutate at a very high rate, and this is also born out by the mapping of the mutations in the different genomes

Seen here - auspice
 

epronovost

Well-Known Member
Correct me if I'm wrong here, but we currently deal with about 130 serotypes of influenza, some of which have been with us for many years

In comparison there are 4311 different genomes of Covid-19 that have been sampled just between the dates of Dec 2019 and Aug 2020, all stemming from that one initial genome in Wuhan

You don't think that's going to greatly complicate vaccine development ?

I do, personally, I also know there are many different approaches to the design of the vaccines ( 130+ different vaccines in development )

And not remarkably mutable ?....I was under the impression that coronavirus mutate at a very high rate, and this is also born out by the mapping of the mutations in the different genomes

Seen here - auspice

It seems you are entirely correct. My info was outdated. There has been an erratum since then.
 

Rational Agnostic

Well-Known Member
You expect magic and fault people when they don't come up with an answer instantly. Real science is not magic.

I don't expect magic. But sometimes amateurs make breakthroughs. Blind trust of the "experts" who have failed at nearly everything to do with this virus while discouraging curiosity and independent thought will lead nowhere.
 
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